3)- Deepali Gupta, Avi W Burstein, Dana C Schwalbe, Kripa Shankar, Salil Varshney, Omprakash Singh, Subhojit Paul, Sean B Ogden, Sherri Osborne-Lawrence, Nathan P Metzger, Corine P Richard, John N Campbell, Jeffrey M Zigman. Ghrelin deletion and conditional ghrelin cell ablation increase pancreatic islet size in mice.The Journal of clinical investigation. 2023, 133 (24):
4)- Sean M Tatum, William L Holland. Germline and conditional ghrelin knockout increases islet size.The Journal of clinical investigation. 2023, 133 (24):
5)- Xiaobo Wang, Shuang Geng, Junchen Meng, Ning Kang, Xinyi Liu, Yanni Xu, Huiyun Lyu, Ying Xu, Xun Xu, Xinrong Song, Bin Zhang, Xin Wang, Nuerdida Nuerbulati, Ze Zhang, Di Zhai, Xin Mao, Ruya Sun, Xiaoting Wang, Ruiwu Wang, Jie Guo, S R Wayne Chen, Xuyu Zhou, Tie Xia, Hai Qi, Xiaoyu Hu, Yan Shi. Foxp3-mediated blockage of ryanodine receptor 2 underlies contact-based suppression by regulatory T cells.The Journal of clinical investigation. 2023, 133 (24):
6)- Deborah A Knight, Shin Foong Ngiow, Ming Li, Tiffany Parmenter, Stephen Mok, Ashley Cass, Nicole M Haynes, Kathryn Kinross, Hideo Yagita, Richard C Koya, Thomas G Graeber, Antoni Ribas, Grant A McArthur, Mark J Smyth. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.The Journal of clinical investigation. 2023, 133 (24):
8)- Amanda Macamo, Jan Beckervordersandforth, Axel Zur Hausen. Metagenome analyses identify human endogenous retrovirus-K113 (HML-2) subtype in glioblastoma.The Journal of clinical investigation. 2023, 133 (24):
11)- Sean Sachdev. A friend in a forest of radiation-immune interactions: BAMBI improves antitumor effects by limiting radioresistance.The Journal of clinical investigation. 2023, 133 (24):
14)- Michael R Schlabach, Sharon Lin, Zachary R Collester, Christopher Wrocklage, Sol Shenker, Conor Calnan, Tianlei Xu, Hugh S Gannon, Leila J Williams, Frank Thompson, Paul R Dunbar, Robert A LaMothe, Tracy E Garrett, Nicholas Colletti, Anja F Hohmann, Noah J Tubo, Caroline P Bullock, Isabelle Le Mercier, Katri Sofjan, Jason J Merkin, Sean Keegan, Gregory V Kryukov, Caroline Dugopolski, Frank Stegmeier, Karrie Wong, Fiona A Sharp, Louise Cadzow, Micah J Benson. Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens.The Journal of clinical investigation. 2023, 133 (24):
16)- Fang Yun Lim, Soo-Young Kim, Karisma N Kulkarni, Rachel L Blazevic, Louise E Kimball, Hannah G Lea, Amanda J Haack, Maia S Gower, Terry Stevens-Ayers, Lea M Starita, Michael Boeckh, Ollivier Hyrien, Joshua T Schiffer, Ashleigh B Theberge, Alpana Waghmare. High-frequency home self-collection of capillary blood correlates IFI27 expression kinetics with SARS-CoV-2 viral clearance.The Journal of clinical investigation. 2023, 133 (23):
18)- André C Carpentier, Denis P Blondin. Human brown adipose tissue is not enough to combat cardiometabolic diseases.The Journal of clinical investigation. 2023, 133 (23):
19)- Anthony L Cunningham, Kerrie J Sandgren, Naomi R Truong. Advances in understanding the mechanism of action of adult vaccines.The Journal of clinical investigation. 2023, 133 (23):
20)- Kim A Tran, Maziar Divangahi. The gift of preexisting immunity for developing an alternative vaccine strategy.The Journal of clinical investigation. 2023, 133 (23):
23)- Aaron M Cypess. Does activating brown fat contribute to important metabolic benefits in humans? Yes!The Journal of clinical investigation. 2023, 133 (23):
24)- Nida Haider, C Ronald Kahn. Interactions between insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts.The Journal of clinical investigation. 2023, :
25)- Imran Khan, Robert E Minto, Christine Kelley-Patteson, Kanhaiya Singh, Lava Timsina, Lily J Suh, Ethan Rinne, Bruce W Van Natta, Colby R Neumann, Ganesh Mohan, Mary Lester, R Jason VonDerHaar, Rana German, Natascia Marino, Aladdin H Hassanein, Gayle M Gordillo, Mark H Kaplan, Chandan K Sen, Marshall E Kadin, Mithun Sinha. Biofilm derived oxylipin 10-HOME mediated immune response in women with breast implants.The Journal of clinical investigation. 2023, :
26)- Abigael Cheruiyot, Jennifer Hollister-Lock, Brooke A Sullivan, Hui Pan, Jonathan M Dreyfuss, Susan Bonner-Weir, Jean E Schaffer. Sustained hyperglycemia specifically targets translation of mRNAs for insulin secretion.The Journal of clinical investigation. 2023, :
27)- Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam C Green, Geoffrey Newcomb, Nuo Sun, Jose A Ovando-Ricardez, Jeffrey C Horowitz, Aneel R Bhagwani, Hu Yang, Tatiana V Kudryashova, Mauricio Rojas, Ana L Mora, Pearlly Yan, Rama K Mallampalli, Elena A Goncharova, David M Eckmann, Laszlo Farkas. RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension.The Journal of clinical investigation. 2023, :
31)- Milagros C Romay, Russell H Knutsen, Feiyang Ma, Ana Mompeón, Gloria E Hernandez, Jocelynda Salvador, Snezana Mirkov, Ayush Batra, David P Sullivan, Daniele Procissi, Samuel Buchanan, Elise Kronquist, Elisa A Ferrante, William A Muller, Jordain Walshon, Alicia Steffens, Kathleen McCortney, Craig Horbinski, Elisabeth Tournier-Lasserve, Adam M Sonabend, Farzaneh A Sorond, MichaelM Wang, Manfred Boehm, Beth A Kozel, M Luisa Iruela-Arispe. Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice.The Journal of clinical investigation. 2023, :
33)- Hye Sun Kuehn, Inga S Sakovich, Julie E Niemela, Agustin A Gil Silva, Jennifer L Stoddard, Ekaterina A Polyakova, Ana Esteve-Sole, Svetlana N Aleshkevich, Tatjana A Uglova, Mikhail V Belevtsev, Vladislav R Vertelko, Tatsiana V Shman, Aleksandra N Kupchinskaya, Jolan E Walter, Thomas A Fleisher, Luigi D Notarangelo, Xiao P Peng, Ottavia Maria Delmonte, Svetlana O Sharapova, Sergio D Rosenzweig. Disease-associated AIOLOS variants lead to immune deficiency/dysregulation by haploinsufficiency and redefine AIOLOS functional domains.The Journal of clinical investigation. 2023, :
34)- Tae Kon Kim, Xue Han, Qianni Hu, Esten N Vandsemb, Carly M Fielder, Junshik Hong, Kwang Woon Kim, Emily F Mason, R Skipper Plowman, Jun Wang, Qi Wang, Jian-Ping Zhang, Ti Badri, Miguel F Sanmamed, Linghua Zheng, Tianxiang Zhang, Jude Alawa, Sang Won Lee, Amer M Zeidan, Stephanie Halene, Manoj M Pillai, Namrata S Chandhok, Jun Lu, Mina L Xu, Steven D Gore, Lieping Chen. PD-1H/VISTA mediates immune evasion in acute myeloid leukemia.The Journal of clinical investigation. 2023, :
35)- Dhanunjay Mukhi, Lingzhi Li, Hongbo Liu, Tomohito Doke, Lakshmi P Kolligundla, Eunji Ha, Konstantin A Klötzer, Amin Abedini, Sarmistha Mukherjee, Junnan Wu, Poonam Dhillon, Hailong Hu, Dongyin Guan, Katsuhiko Funai, Kahealani Uehara, Paul M Titchenell, Joseph A Baur, Kathryn E Wellen, Katalin Susztak. ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules.The Journal of clinical investigation. 2023, :
36)- Kelsey R van Straalen, Feiyang Ma, Pei-Suen Tsou, Olesya Plazyo, Mehrnaz Gharaee-Kermani, Marta Calbet, Xianying Xing, Mrinal K Sarkar, Ranjitha Uppala, Paul W Harms, Rachael Wasikowski, Lina Nahlawi, Mio Nakamura, Milad Eshaq, Cong Wang, Craig J Dobry, Jeffrey H Kozlow, Jill R Cherry-Bukowiec, William D Brodie, Kerstin Wolk, Özge Uluckan, Megan N Mattichak, Matteo Pellegrini, Robert L Modlin, Emanual Maverakis, Robert Sabat, J Michelle Kahlenberg, Allison C Billi, Lam C Tsoi, Johann E Gudjonsso. Single cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.The Journal of clinical investigation. 2023, :
38)- Fan He, Angelo B A Laranjeira, Tim Kong, Shuyang Lin, Katrina J Ashworth, Alice Liu, Nina M Lasky, Daniel Ac Fisher, Maggie J Cox, Mary C Fulbright, Lilian A Antunes Heck, LaYow C Yu, Molly Brakhane, Bei Gao, Stephen M Sykes, Angelo D'Alessandro, Jorge A Di Paola, Stephen T Oh. Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms.The Journal of clinical investigation. 2023, :
40)- Christopher Berlin, Bernhard Mauerer, Pierre Cauchy, Jost Luenstedt, Roman Sankowski, Lisa Marx, Reinhild Feuerstein, Luisa Schäfer, Florian R Greten, Marina Pesic, Olaf Groß, Marco Prinz, Naomi Rühl, Laura Miketiuk, Dominik Jauch, Claudia Laessle, Andreas Jud, Esther A Biesel, Hannes P Neeff, Stefan Fichtner-Feigl, Philipp A Holzner, Rebecca Kesselring. Single-cell deconvolution reveals high lineage- and location-dependent heterogeneity in mesenchymal multivisceral stage IV colorectal cancer.The Journal of clinical investigation. 2023, :
42)- Ryan B Day, Julia A Hickman, Ziheng Xu, Casey Ds Katerndahl, Francesca Ferraro, Sai Mukund Ramakrishnan, Petra Erdmann-Gilmore, Robert W Sprung, Yiling Mi, R Reid Townsend, Christopher A Miller, Timothy J Ley. Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB::MYH11 oncofusion protein.The Journal of clinical investigation. 2023, :
43)- Jianrui Song, Yanling Zhang, Ryan A Frieler, Anthony Andren, Sherri C Wood, Daniel J Tyrrell, Peter Sajjakulnukit, Jane C Deng, Costas A Lyssiotis, Richard M Mortensen, Morgan Salmon, Daniel R Goldstein. Itaconate suppresses atherosclerosis by activating a Nrf2-dependent anti-inflammatory response in macrophages in mice.The Journal of clinical investigation. 2023, :
44)- Yohannes A Mebratu, Jane T Jones, Congjian Liu, Zerihun H Negasi, Mizanur Rahman, Joselyn Rojas-Quintero, George T O'Connor, Wei Gao, Josee Dupuis, Michael H Cho, Augusto A Litonjua, Scott Randell, Yohannes Tesfaigzi. Bik promotes proteasomal degradation to control low grade inflammation.The Journal of clinical investigation. 2023, :
45)- Brenda J Seymour, Brandon Trent, Brendan E Allen, Adam J Berlinberg, Jimmy Tangchittsumran, Widian K Jubair, Meagan E Chriswell, Sucai Liu, Alfredo Ornelas, Andrew Stahly, Erica E Alexeev, Alexander S Dowdell, Sunny L Sneed, Sabrina Fechtner, Jennifer M Kofonow, Charles E Robertson, Stephanie M Dillon, Cara C Wilson, Robert M Anthony, Daniel N Frank, Sean P Colgan, Kristine A Kuhn. Microbiota-dependent indole production stimulates the development of collagen-induced arthritis in mice.The Journal of clinical investigation. 2023, :
46)- Manale El Kharbili, Sarah K Sasse, Lynn Sanford, Sean Jacobson, Katja Aviszus, Arnav Gupta, Claire J Guo, Susan M Majka, Robin D Dowell, Anthony N Gerber, Russell P Bowler, Fabienne Gally. Noncoding SNPs decrease expression of FABP5 during COPD exacerbations.The Journal of clinical investigation. 2023, :
47)- Jackelyn R Raymundo, Hui Zhang, Giovanni Smaldone, Wenjuan Zhu, Kathleen E Daly, Benjamin J Glennon, Giovanni Pecoraro, Marco Salvatore, William A Devine, Cecilia W Lo, Luigi Vitagliano, Alexander G Marneros. KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions and their impairment causes aplasia cutis.The Journal of clinical investigation. 2023, :
48)- Susan M Lin, Ryan Rue, Alexander R Mukhitov, Akansha Goel, Maria C Basil, Kseniya Obraztsova, Apoorva Babu, Slaven Crnkovic, Owen Ledwell, Laura T Ferguson, Joseph D Planer, Ana N Nottingham, Kanth Swaroop Vanka, Carly J Smith, Edward Cantu Iii, Grazyna Kwapiszewska, Edward E Morrisey, Jillian F Evans, Vera P Krymskaya. Hyperactive mTORC1 in lung mesenchyme induces endothelial cell dysfunction and pulmonary vascular remodeling.The Journal of clinical investigation. 2023, :
50)- Kumiko Nishio, Lise Pasquet, Kaddy Camara, Julia DiSapio, Shingo Kato, Kevin S Hsu, Anja Bloom, Stewart K Richardson, Joshua A Welsh, Tianbo Jiang, Jennifer C Jones, Susanna Cardell, Hiroshi Watarai, Masaki Terabe, Purevdorj B Olkhanud, Amy R Howell, Jay A Berzofsky. Lysosomal processing of sulfatide analogues alters target NKT cell specificity and immune responses in cancer.The Journal of clinical investigation. 2023, :