Clinical and Translational Science: 2023, vol: , issue:
- 1)- Maria E Trujillo, Surya Ayalasomayajula, Robert O Blaustein, Ferdous Gheyas. Vericiguat, a novel sGC stimulator: Mechanism of action, clinical, and translational science. Clinical and translational science. 2023, 16 (12): 2458-2466
Cited : 9Read More - 2)- Chiao Xin Lim, Alistair Bozkurt, Zi Yue Chen, Abbey Hird, Joanne Wickens, Smaro Lazarakis, Safeera Y Hussainy, Marliese Alexander. Healthcare professionals' and consumers' knowledge, attitudes, perspectives, and education needs in oncology pharmacogenomics: A systematic review. Clinical and translational science. 2023, 16 (12): 2467-2482Cited : 3Read More
- 3)- Nicolas Hohmann, Martin Ronald Sprick, Moritz Pohl, Azaz Ahmed, Jürgen Burhenne, Marietta Kirchner, Lucian Le Cornet, Markus Kratzmann, Jacek Hajda, Albrecht Stenzinger, Karen Steindorf, Stefan Delorme, Heinz-Peter Schlemmer, Sabine Riethdorf, Ron van Schaik, Klaus Pantel, Jens Siveke, Thomas Seufferlein, Dirk Jäger, Walter E Haefeli, Andreas Trumpp, Christoph Springfeld. Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy. Clinical and translational science. 2023, 16 (12): 2483-2493Cited : 0Read More
- 4)- Jacob M van Laar, Alejhandra Lei, Mary Safy-Khan, Joachim Almquist, Graham Belfield, Karl Edman, Lisa Öberg, Bastian R Angermann, Inken Dillmann, Pia Berntsson, Damla Etal, Ian Dainty, Carol Astbury, Maria G Belvisi, Szilárd Nemes, Adam Platt, Susanne Prothon, Sara Samuelsson, Petter Svanberg, Christina Keen, . AZD9567 versus prednisolone in patients with active rheumatoid arthritis: A phase IIa, randomized, double-blind, efficacy, and safety study. Clinical and translational science. 2023, 16 (12): 2494-2506Cited : 1Read More
- 5)- LiBo Zhao, YingHui Gao, WeiHao Xu, KaiLiang Li, Lin Liu, Li Fan. Factors influencing new-onset hypertension in elderly patients with obstructive sleep apnea: A multicenter cohort study. Clinical and translational science. 2023, 16 (12): 2507-2518Cited : 2Read More
- 6)- Xuan Huang, Junmin Li, Xiaoying Pang, Jialei Zhu, Jiaqian Pan, Yueyan Li, Jing Tang. Gene polymorphism and prediction of toxicity to platinum-based chemotherapy in patients with gynecologic cancer. Clinical and translational science. 2023, 16 (12): 2519-2529Cited : 0Read More
- 7)- Andreas Becker, Axel Krebs-Brown, Claudia Vetter, Tanja Reuter, Almudena Rodriguez-Gutierrez, Xiaoli You, Michael Lissy. Phase I crossover study of DNA-protein kinase inhibitor peposertib in healthy volunteers: Effect of food and pharmacokinetics of an oral suspension. Clinical and translational science. 2023, 16 (12): 2628-2639Cited : 2Read More
- 8)- John E McKinnon, Joel Santiaguel, Claudia Murta de Oliveira, Dongzi Yu, Mukhy Khursheed, Flavie Moreau, Lena Klopp-Schulze, Jamie Shaw, Sanjeev Roy, Amy H Kao, . Enpatoran in COVID-19 pneumonia: Safety and efficacy results from a phase II randomized trial. Clinical and translational science. 2023, 16 (12): 2640-2653Cited : 1Read More
- 9)- Paloma Moraga Alapont, Paula Prieto, Mikel Urroz, María Jiménez, Antonio J Carcas, Alberto M Borobia. Evaluation of factors associated with recruitment rates in early phase clinical trials based on the European Clinical Trials Register data. Clinical and translational science. 2023, 16 (12): 2654-2664Cited : 0Read More
- 10)- Ruth Lizzeth Madera-Sandoval, Arturo Cérbulo-Vázquez, Lourdes Andrea Arriaga-Pizano, Graciela Libier Cabrera-Rivera, Edna Basilio-Gálvez, Patricia Esther Miranda-Cruz, María Teresa García de la Rosa, Jessica Lashkmin Prieto-Chávez, Silvia Vanessa Rivero-Arredondo, Alonso Cruz-Cruz, Daniela Rodríguez-Hernández, María Eugenia Salazar-Ríos, Enrique Salazar-Ríos, Esli David Serrano-Molina, Roberto Carlos De Lira-Barraza, Abel Humberto Villanueva-Compean, Alejandra Esquivel-Pineda, Rubén Ramírez-Mont. Potential biomarkers for fatal outcome prognosis in a cohort of hospitalized COVID-19 patients with pre-existing comorbidities. Clinical and translational science. 2023, 16 (12): 2687-2699Cited : 0Read More
- 11)- Sarah Glewis, Mei Krishnasamy, Senthil Lingaratnam, Sam Harris, Craig Underhill, Chloe Georgiou, Mark Warren, Robert Campbell, Maarten IJzerman, Mussab Fagery, Ian Campbell, Jennifer H Martin, Jeanne Tie, Marliese Alexander, Michael Michael. Patient and healthcare professional acceptability of pharmacogenetic screening for DPYD and UGT1A1: A cross sectional survey. Clinical and translational science. 2023, 16 (12): 2700-2708Cited : 0Read More
- 12)- Apichot So-Ngern, Supunnee Jirajariyavej, Huttaya Thuncharoon, Nuttha Khunthupat, Teerachai Chantarojanasiri, Preecha Montakantikul. A randomized, controlled trial of prulifloxacin as conversion therapy after intravenous carbapenem in the treatment of acute pyelonephritis caused by third generation cephalosporin resistant pathogens: A pilot study. Clinical and translational science. 2023, 16 (12): 2709-2718Cited : 0Read More
- 13)- Diego Paine-Cabrera, Lisa K Harvey, Dakota R Robarts, Michele T Pritchard, John Thyfault, Steven A Weinman, Udayan Apte, Voytek Slowik. Leukocyte cell-derived chemotaxin 2 correlates with pediatric non-alcoholic fatty liver disease. Clinical and translational science. 2023, 16 (12): 2719-2728Cited : 2Read More
- 14)- Robert Greite, Sebastian Schott, Li Wang, Lukas Gohlke, Kirill Kreimann, Katja Derlin, Marcel Gutberlet, Martina Schmidbauer, Andreas Leffler, Igor Tudorache, Jawad Salman, Fabio Ius, Ruslan Natanov, Christine Fegbeutel, Axel Haverich, Ralf Lichtinghagen, Anne M Hüsing, Sibylle von Vietinghoff, Roland Schmitt, Nelli Shushakova, Song Rong, Hermann Haller, Kai M Schmidt-Ott, Magnus Gram, Vijith Vijayan, Irina Scheffner, Wilfried Gwinner, Stephan Immenschuh. Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia. Clinical and translational science. 2023, 16 (12): 2729-2743Cited : 3Read More
- 15)- Michael Z Liao, Rong Deng, Leonid Gibiansky, Tong Lu, Priya Agarwal, Randall Dere, Calvin Lee, Jamie Hirata, Charles Herbaux, Gilles Salles, Chunze Li, Dale Miles. Ethnic sensitivity assessment: Polatuzumab vedotin pharmacokinetics in Asian and non-Asian patients with previously untreated diffuse large B-cell lymphoma in POLARIX. Clinical and translational science. 2023, 16 (12): 2744-2755Cited : 1Read More
- 16)- Joseph Kotsybar, Susan Hakeem, Lei Zhang, Wenlei Jiang. Global harmonization of immediate-release solid oral drug product bioequivalence recommendations and the impact on generic drug development. Clinical and translational science. 2023, 16 (12): 2756-2764Cited : 0Read More
- 17)- Shuo Zheng, Apparao B Kummarapurugu, Gamze B Bulut, Aamer Syed, Le Kang, Judith A Voynow. Neutrophil elastase activates the release of extracellular traps from COPD blood monocyte-derived macrophages. Clinical and translational science. 2023, 16 (12): 2765-2778Cited : 2Read More
- 18)- Ya Gao, Xuan Liu, Beibei Xu, Ximeng Zhang, Yiqing Wang, Jianqiang Ni, Yi Yang. Effect of collateral circulation in patients with multiple craniocervical artery stenoses. Clinical and translational science. 2023, 16 (12): 2779-2790Cited : 0Read More
- 19)- Shuling Yan, Xia Zhao, Qiushi Xie, Weijuan Du, Qingyang Ma, Tongkang Zhu, Huan Deng, Lei Qian, Shirui Zheng, Yimin Cui. Pharmacokinetic/LDL-C and exposure-response analysis of tafolecimab in Chinese hypercholesterolemia patients: Results from phase I, II, and III studies. Clinical and translational science. 2023, 16 (12): 2791-2803Cited : 2Read More
- 20)- Elisabeth Bakker, Viktoriia Starokozhko, Jet W M Kraaijvanger, Hiddo J L Heerspink, Peter G M Mol. Precision medicine in regulatory decision making: Biomarkers used for patient selection in European Public Assessment Reports from 2018 to 2020. Clinical and translational science. 2023, 16 (11): 2394-2412Cited : 3Read More
- 21)- Michael L Granda, Weize Huang, Catherine K Yeung, Nina Isoherranen, Bryan Kestenbaum. Predicting complex kidney drug handling using a physiologically-based pharmacokinetic model informed by biomarker-estimated secretory clearance and blood flow. Clinical and translational science. 2023, : Cited : 0Read More
- 22)- Warunee Mingpun, Abhasnee Sobhonslidsuk, Supatat Chumnumwat. Optimal resting heart rate and ascites-related death in patients with cirrhosis and ascites using nonselective beta-blockers (ORCA). Clinical and translational science. 2023, : Cited : 0Read More
- 23)- Jeffrey R Proctor, Harvey Wong. Time-dependent clearance can confound exposure-response analysis of therapeutic antibodies: A comprehensive review of the current literature. Clinical and translational science. 2023, : Cited : 3Read More
- 24)- Katherine L Chen, Carlos Irwin A Oronce, Nancy E Calderón, Katherine L Kahn. Academic seminars as tool for clinical and translational science education and dissemination: Perceptions and priorities in the COVID-19 era. Clinical and translational science. 2023, : Cited : 0Read More
- 25)- Kerem Teralı, Ayberk Türkyılmaz, Safiye Güneş Sağer, Alper Han Çebi. Prediction of molecular phenotypes for novel SCN1A variants from a Turkish genetic epilepsy syndromes cohort and report of two new patients with recessive Dravet syndrome. Clinical and translational science. 2023, : Cited : 1Read More
- 26)- Jackson K Mukonzo, Helen Byomire Ndagije, George Tsey Sabblah, Wangui Mathenge, David A Price, Thaddeus H Grasela. Expanding regulatory science: Regulatory complementarity and reliance. Clinical and translational science. 2023, : Cited : 0Read More
- 27)- Woorim Kim, Go Woon Lee, Nuga Rhee, Kyung Hyun Min, Jun Hyeob Kim, Jin Yeon Gil, Song Yi Kim, Ji Min Han, Kyung Eun Lee. Risk factors for hyperglycemia in COVID-19 patients treated with remdesivir. Clinical and translational science. 2023, : Cited : 1Read More
- 28)- Kefeng Sun, Martha Fournier, Aimee K Sundberg, Ivy H Song. Maribavir: Mechanism of action, clinical, and translational science. Clinical and translational science. 2023, : Cited : 2Read More
- 29)- Ana Casajús, Pablo Zubiaur, Enrique Alday, Paula Soria-Chacartegui, Miriam Saiz-Rodriguez, Lara Gutierrez, Catalina Aragonés, Diana Campodónico, Antía Gómez-Fernández, Marcos Navares-Gómez, Gonzalo Villapalos-García, Gina Mejía-Abril, Dolores Ochoa, Francisco Abad-Santos. Impact of CYP2D6 and CYP2B6 phenotypes on the response to tramadol in patients with acute post-surgical pain. Clinical and translational science. 2023, : Cited : 0Read More
- 30)- Lan Gao, Diksha Kaushik, Brian A Van Tine, Matthew A Ingham, Steven Attia, Christian F Meyer, Gary K Schwartz, Pius Maliakal, John D Baird, Jiyuan Ma, Rosemary Barrett, Dhiren D'Silva, Kylie O'Keefe, Ronald Kong. Pharmacokinetics of Dacarbazine and Unesbulin and CYP1A2-Mediated Drug Interactions in Patients With Leiomyosarcoma. Clinical and translational science. 2023, : Cited : 0Read More
- 31)- Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk. Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science. 2023, : Cited : 8Read More
- 32)- Sharyn D Baker, William D Figg. In Memoriam Michelle A. Rudek (1972 - 2023). Clinical and translational science. 2023, : Cited : 0Read More
- 33)- Mohamed-Eslam F Mohamed, Yuli Qian, Ronilda D'Cunha, Teresa Sligh, Laura K Ferris, Ann Eldred, Gweneth F Levy, Shuai Hao, Shashikanth Gannu, David G Rizzo, Wei Liu, Sasha Jazayeri, Howard Sofen, Roberto Carcereri De Prati. Pharmacokinetics, safety, and efficacy of cedirogant from phase I studies in healthy participants and patients with chronic plaque psoriasis. Clinical and translational science. 2023, : Cited : 4Read More
- 34)- Ruolun Qiu, Kari Fonseca, Arthur Bergman, Jian Lin, David Tess, Lauren Newman, Alia Fahmy, Zivile Useckaite, Andrew Rowland, Manoli Vourvahis, David Rodrigues. Study of the ketohexokinase inhibitor PF-06835919 as a clinical cytochrome P450 3A inducer: Integrated use of oral midazolam and liquid biopsy. Clinical and translational science. 2023, : Cited : 0Read More
- 35)- Wonsuk Shin, Min Young Park, Jongwoo Kim, Jihyeon Kim, Jun Hee Nam, Jongwon Choi, A-Young Yang, Hyounggyoon Yoo, Yil-Seob Lee, Anhye Kim. No drug-drug interactions between selective prolyl-trna synthetase inhibitor, bersiporocin, and pirfenidone or nintedanib in healthy participants. Clinical and translational science. 2023, : Cited : 0Read More
- 36)- Simone Grobbelaar, Anne E Mercier, Iman van den Bout, Chrisna Durandt, Michael S Pepper. Considerations for enhanced mesenchymal stromal/stem cell myogenic commitment in vitro. Clinical and translational science. 2023, : Cited : 2Read More
- 37)- Lily Yuan, Motiur Rahman, John Concato. Comparison of two assessments of real-world data and real-world evidence for regulatory decision-making. Clinical and translational science. 2023, : Cited : 1Read More
- 38)- Caroline Falkenberg, Christina Bartholdy, Janne Koch, Martin Fitzner Toft, Søren Skov, Camilla Hartmann Friis Hansen, Axel Kornerup Hansen. Induction of CD8+ Immune Memory and Enhanced Inflammation in a Skin Inflammation Model through Pre-Immunization with Inactivated Pathogens. Clinical and translational science. 2023, : Cited : 2Read More
- 39)- Bin Han, Xu Man, Jian Ding, Yuzhu Li, Xintao Tian, Xuelian Zhu, Jiang Yu, Jinping Sun. Subtyping treatment response of tirofiban in acute ischemic stroke based on neuroimaging features. Clinical and translational science. 2023, : Cited : 0Read More
- 40)- Hannah G Hoban, Tiffany A Yip, Joanna C Chau, Jeannette T Bensen, Lauren R Desrosiers, Candice R Finnila, Lucia A Hindorff, Nicole R Kelly, Frances L Lynch, Bradley A Rolf, Hadley S Smith, Melissa P Wasserstein, Kristen Hassmiller Lich. The motivation and process for developing a consortium-wide time and motion study to estimate resource implications of innovations in the use of genome sequencing to inform patient care. Clinical and translational science. 2023, : Cited : 0Read More
- 41)- Luming Wang, Danping Hu, Jinming Xu, Jian Hu, Yifei Wang. Complex in vitro Model: A Transformative Model in Drug Development and Precision Medicine. Clinical and translational science. 2023, : Cited : 2Read More
- 42)- Viktoria Koroknai, István Szász, Krisztina Jámbor, Margit Balázs. Expression pattern of osteopontin isoforms in malignant melanoma cell lines. Clinical and translational science. 2023, : Cited : 1Read More
- 43)- Julie Schjødtz Hansen, Fernando Boix, Jørgen Bo Hasselstrøm, Lambert Kristiansen Sørensen, Mads Kjolby, Stefan Gustavsen, Rikke Middelhede Hansen, Thor Petersen, Finn Sellebjerg, Helge Kasch, Peter Vestergaard Rasmussen, Nanna Brix Finnerup, Eva Aggerholm Saedder, Kristina Bacher Svendsen. Pharmacokinetics and pharmacodynamics of cannabis-based medicine in a patient population included in a randomized, placebo-controlled, clinical trial. Clinical and translational science. 2023, : Cited : 4Read More
- 44)- David Damoiseaux, Alfred H Schinkel, Jos H Beijnen, Alwin D R Huitema, Thomas P C Dorlo. Predictability of human exposure by human-CYP3A4-transgenic mouse models: A meta-analysis. Clinical and translational science. 2023, : Cited : 0Read More
- 45)- Christelle Lteif, Elizabeth Eddy, Joshua Terrell, Larisa H Cavallari, John Malaty, Julio D Duarte. Feasibility of preemptive pharmacogenetic testing and improvement of medication treatment satisfaction among medically underserved patients. Clinical and translational science. 2023, : Cited : 2Read More
- 46)- Agnes Hincelin-Mery, Xavier Nicolas, Cathy Cantalloube, Robert Pomponio, Pascale Lewanczyk, Myriam Benamor, Dimitry Ofengeim, Emmanuel Krupka, Jennifer Hsiao-Nakamoto, Amy Eastenson, Nazem Atassi. Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants. Clinical and translational science. 2023, : Cited : 3Read More
- 47)- Siak-Leng Choi, Delphine Valente, Angela Virone-Oddos, Christine Mauriac. Developing a mechanistic translational PK/PD model for a trifunctional NK cell engager to predict the first-in-human dose for acute myeloid leukemia. Clinical and translational science. 2023, : Cited : 3Read More
- 48)- Mohamed-Eslam F Mohamed, Sumit Bhatnagar, Julie M Parmentier, Priscila Nakasato, Peter Wung. Upadacitinib: Mechanism of action, clinical, and translational science. Clinical and translational science. 2023, : Cited : 16Read More
- 49)- Nicole Llewellyn, Eric J Nehl, Gaurav Dave, Deborah DiazGranados, David Flynn, Deborah Fournier, Verónica Hoyo, Clara Pelfrey, Shannon Casey. Translation in Action: Influence, Collaboration, and Evolution of COVID-19 Research with Clinical and Translational Science Awards Consortium Support. Clinical and translational science. 2023, : Cited : 0Read More
- 50)- Chao Li, ChengXin Deng, Ping Wu, KaiFan Liu, Xin Huang, MingMin Li, XiaoMei Chen, SuXia Geng, PeiLong Lai, JianYu Weng, Xin Du. Outcomes of intermediate or high-risk CMML patients treated with HMAs combined with Venetoclax: a single center experience. Clinical and translational science. 2023, : e13711Cited : 1Read More
